MeSH Browser

MeSH Heading: S100 Calcium-Binding Protein A4
Tree Number(s): D12.776.157.125.750.813
Unique ID: D000071999
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071999
Scope Note: An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
Entry Term(s): Calvasculin Protein; Fibroblast-Specific Protein 1; Metastasin Protein; Placental Calcium-Binding Protein; S100A4 Protein
Registry Number: 0
Previous Indexing: Calcium-Binding Proteins (1992-2016); S100 Proteins (2003-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000616196
Registry Number: 0
Scope Note: An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
Terms: S100 Calcium-Binding Protein A4 Preferred Term
Term UI T000897814
Date03/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); Metastasin Protein
Term UI T000897818
Date03/28/2016
LexicalTag NON
ThesaurusID NLM (2017); Placental Calcium-Binding Protein
Term UI T000897816
Date03/28/2016
LexicalTag NON
ThesaurusID NLM (2017); Calvasculin Protein
Term UI T000897817
Date03/28/2016
LexicalTag NON
ThesaurusID NLM (2017); Fibroblast-Specific Protein 1
Term UI T000900392
Date05/05/2016
LexicalTag NON
ThesaurusID NLM (2017); S100A4 Protein
Term UI T000897815
Date03/28/2016
LexicalTag ABX
ThesaurusID NLM (2017)

S100 Calcium-Binding Protein A4 MeSH Descriptor Data 2023