NLM Logo

Disks Large Homolog 4 Protein MeSH Descriptor Data 2025


MeSH Heading
Disks Large Homolog 4 Protein
Tree Number(s)
D08.811.913.696.650.450.750
D12.644.360.265
D12.776.476.265
D12.776.543.219
D12.776.631.224
Unique ID
D000076122
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000076122
Scope Note
A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.
Entry Term(s)
Discs Large Homolog 4 Protein
PSD-95 Protein
PSD95 Protein
Postsynaptic Density Protein 95
SAP-90 Protein
SAP90 Protein
Synapse-Associated Protein 90
Previous Indexing
Intracellular Signaling Peptides and Proteins (2005-2017)
Membrane Proteins (2005-2017)
See Also
SAP90-PSD95 Associated Proteins
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/06/29
Disks Large Homolog 4 Protein Preferred
page delivered in 0.287s