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Carbonic Anhydrase IX MeSH Descriptor Data 2023


MeSH Heading
Carbonic Anhydrase IX
Tree Number(s)
D08.811.520.241.300.150.450
D12.776.543.178
D23.050.285.196
Unique ID
D000071231
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071231
Scope Note
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
Entry Term(s)
CAIX Protein
Carbonic Anhydrase 9
Registry Number
EC 4.2.1.1
Previous Indexing
Antigens, Neoplasm (1994-2016)
Carbonic Anhydrases (1994-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/25
Carbonic Anhydrase IX Preferred
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