- Concept UI
- M000613753
- Registry Numbers
- EC 4.2.1.1
- Scope Note
- A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
- Terms
-
Carbonic Anhydrase IX
Preferred Term
Term UI
T000893976
Date01/22/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
Carbonic Anhydrase 9
Term UI
T000893977
Date01/22/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
CAIX Protein
Term UI
T000893978
Date01/22/2016
LexicalTag
NON
ThesaurusID
NLM (2017)