MeSH Browser

MeSH Heading: Peroxisomal Biogenesis Factor 2
Tree Number(s): D12.776.157.635.500; D12.776.543.689
Unique ID: D000074428
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074428
Scope Note: A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.
Entry Term(s): PMP35; Peroxin-2; Peroxisomal Membrane Protein 35; Peroxisome Assembly Factor-1; Peroxisome Biogenesis Factor 2
See Also: RING Finger Domains
Public MeSH Note: 2018; see PEROXISOME ASSEMBLY FACTOR-1 1991-2017; PEROXISOMAL BIOGENESIS FACTOR 2 was indexed under MEMBRANE PROTEINS 1991-2017
History Note: 2018 (1991)
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0185701
Scope Note: A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.
Terms: Peroxisomal Biogenesis Factor 2 Preferred Term
Term UI T000915885
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (2018); Peroxisome Assembly Factor-1
Term UI T000915886
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (1991); Peroxisomal Membrane Protein 35
Term UI T000915887
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (1991); Peroxisome Biogenesis Factor 2
Term UI T000915888
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (2018); Peroxin-2
Term UI T000915889
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (1991); PMP35
Term UI T215703
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (1991)

Peroxisomal Biogenesis Factor 2 MeSH Descriptor Data 2025