MeSH Browser

MeSH Heading: Chemokine CX3CL1
Tree Number(s): D12.644.276.374.200.130.500; D12.776.467.374.200.130.500; D12.776.543.193; D23.125.300.130.500; D23.469.200.130.500; D23.529.374.200.130.500
Unique ID: D054428
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054428
Scope Note: A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.
Entry Term(s): CX3CL1 Chemokine; Chemokine (C-X3-C Motif) Ligand 1; Fractalkine; Neurotactin
Public MeSH Note: 2008; CHEMOKINE (C-X3-C MOTIF) LIGNAND 1 (now CHEMOKINE CX2CL1) was indexed under CHEMOKINES, CX3C 2002-2007, under CHEMOKINES, CXC 1997-2001 & under CHEMOKINES 1997
History Note: 2008(1997)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0272052
Scope Note: A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.
Terms: Chemokine CX3CL1 Preferred Term
Term UI T687903
Date12/15/2006
LexicalTag ABX
ThesaurusID NLM (2008); Chemokine (C-X3-C Motif) Ligand 1
Term UI T683452
Date10/11/2006
LexicalTag NON
ThesaurusID NLM (2008); CX3CL1 Chemokine
Term UI T687904
Date12/15/2006
LexicalTag ABX
ThesaurusID NLM (2008); Fractalkine
Term UI T302057
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); Neurotactin
Term UI T683453
Date10/11/2006
LexicalTag NON
ThesaurusID NLM (2008)

Chemokine CX3CL1 MeSH Descriptor Data 2025