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Amyloid beta-Protein Precursor MeSH Descriptor Data 2025


MeSH Heading
Amyloid beta-Protein Precursor
Tree Number(s)
D12.776.049.407.249
D12.776.543.039
D12.776.811.050
D12.776.815.468.500
Unique ID
D016564
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016564
Scope Note
A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.
Entry Version
ABPP
Entry Term(s)
Amyloid A4 Protein Precursor
Amyloid Protein Precursor
Amyloid beta Precursor Protein
Protease Nexin 2
Protease Nexin II
beta-Amyloid Protein Precursor
Previous Indexing
Amyloid (1988-1991)
Protein Precursors (1988-1991)
Public MeSH Note
92; AMYLOID BETA-PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN 1990-91 and AMYLOID & PROTEIN PRECURSORS 1988-91; AMYLOID A4 PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN PRECURSOR 1993-94, AMYLOID BETA-PROTEIN 1991-92, PROTEIN PRECURSORS 1987-92, & AMYLOID 1987-90
Online Note
use AMYLOID BETA-PROTEIN PRECURSOR (NM) to search AMYLOID BETA-PROTEIN PRECURSOR 1988-91 & AMYLOID A4 PROTEIN PRECURSOR 1987-94
History Note
92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2022/07/12
Amyloid beta-Protein Precursor Preferred
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