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Pro-Opiomelanocortin MeSH Descriptor Data 2023


MeSH Heading
Pro-Opiomelanocortin
Tree Number(s)
D06.472.699.327.935
D06.472.699.631.525.600
D12.644.400.400.935
D12.644.548.365.935
D12.644.548.691.525.690
D12.776.631.650.405.935
D12.776.811.800
Unique ID
D011333
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011333
Scope Note
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Entry Term(s)
ACTH-Endorphin Precursor
ACTH-beta-Lipotropin Precursor
Corticotropin-beta-Lipotropin Precursor
Endorphin-ACTH Precursor
Opiocortin
POMC
Pre-POMC
Pre-pro-opiocortin
Preproopiomelanocortin
Pro-ACTH-Endorphin
Pro-Opio-Melanocortin
Pro-Opiocortin
Proopiocortin
Proopiomelanocortin
Registry Number
66796-54-1
Related Numbers
76775-14-9
78321-08-1
CAS Type 1 Name
Opiomelanocortin, pro-
Previous Indexing
Pituitary Hormones, Anterior (1966-1984)
Protein Precursors (1973-1984)
Public MeSH Note
1985; PRE-PRO-OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN & PROTEIN PRECURSORS 1980-2007; OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN 1987-2007
History Note
1985
Date Established
1985/01/01
Date of Entry
1984/05/30
Revision Date
2015/11/24
Pro-Opiomelanocortin Preferred
Preproopiomelanocortin Narrower
Opiocortin Narrower
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