MeSH Browser

MeSH Heading: gamma-MSH
Tree Number(s): D06.472.699.327.935.524; D06.472.699.327.935.531.750.115; D06.472.699.631.525.600.524; D06.472.699.631.525.600.531.750.115; D12.644.400.400.935.524; D12.644.400.400.935.531.750.115; D12.644.400.460.115; D12.644.548.365.935.524; D12.644.548.365.935.531.750.115; D12.644.548.691.525.690.524; D12.644.548.691.525.690.531.750.115; D12.776.631.650.405.935.524; D12.776.631.650.405.935.531.750.115; D12.776.631.650.460.115
Unique ID: D019825
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019825
Scope Note: An 11-amino acid peptide derived from the N-terminal fragment of pro-opiomelanocortin (POMC). Gamma-MSH stimulates adrenal steroidogenesis and has an regulatory role in the cardiovascular and the renal systems.
Entry Term(s): MSH, gamma; Melanocyte-Stimulating Hormone, gamma; N-POMC; N-Terminal Peptide of POMC (NPP); Pro-gamma-MSH; Pro-gamma-Melanotropin; gamma-Melanocyte-Stimulating Hormone; gamma-Melanotropin; gamma-Melanotropin Precursor; gamma1-MSH; gamma2-MSH; gamma3-MSH
Pharm Action: Hormones
Registry Numbers: 0
Public MeSH Note: 1998; N-POMC was indexed under PEPTIDE FRAGMENTS & PRO-OPIOMELANOCORTIN 1981-2006
History Note: 1998 (1981)
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Hypothalamic Hormones [D06.472.699.327]
      - Pro-Opiomelanocortin [D06.472.699.327.935]
        
        alpha-Endorphin [D06.472.699.327.935.119]
        
        alpha-MSH [D06.472.699.327.935.179]
        
        beta-Endorphin [D06.472.699.327.935.239]
        
        beta-Lipotropin [D06.472.699.327.935.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D06.472.699.327.935.498]
        
        gamma-Endorphin [D06.472.699.327.935.505]
        
        gamma-Lipotropin [D06.472.699.327.935.518]
        
        gamma-MSH [D06.472.699.327.935.524]
        
        Melanocortins [D06.472.699.327.935.531]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Hypothalamic Hormones [D06.472.699.327]
      - Pro-Opiomelanocortin [D06.472.699.327.935]
        
        Melanocortins [D06.472.699.327.935.531]
        
        Melanocyte-Stimulating Hormones [D06.472.699.327.935.531.750]
        
        alpha-MSH [D06.472.699.327.935.531.750.050]
        
        beta-MSH [D06.472.699.327.935.531.750.075]
        
        gamma-MSH [D06.472.699.327.935.531.750.115]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Pituitary Hormones [D06.472.699.631]
      - Pituitary Hormones, Anterior [D06.472.699.631.525]
        
        Pro-Opiomelanocortin [D06.472.699.631.525.600]
        
        alpha-Endorphin [D06.472.699.631.525.600.119]
        
        alpha-MSH [D06.472.699.631.525.600.179]
        
        beta-Endorphin [D06.472.699.631.525.600.239]
        
        beta-Lipotropin [D06.472.699.631.525.600.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D06.472.699.631.525.600.498]
        
        gamma-Endorphin [D06.472.699.631.525.600.505]
        
        gamma-Lipotropin [D06.472.699.631.525.600.518]
        
        gamma-MSH [D06.472.699.631.525.600.524]
        
        Melanocortins [D06.472.699.631.525.600.531]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Pituitary Hormones [D06.472.699.631]
      - Pituitary Hormones, Anterior [D06.472.699.631.525]
        
        Pro-Opiomelanocortin [D06.472.699.631.525.600]
        
        Melanocortins [D06.472.699.631.525.600.531]
        
        Melanocyte-Stimulating Hormones [D06.472.699.631.525.600.531.750]
        
        alpha-MSH [D06.472.699.631.525.600.531.750.050]
        
        beta-MSH [D06.472.699.631.525.600.531.750.075]
        
        gamma-MSH [D06.472.699.631.525.600.531.750.115]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Neuropeptides [D12.644.400]
    - Hypothalamic Hormones [D12.644.400.400]
      - Pro-Opiomelanocortin [D12.644.400.400.935]
        
        alpha-Endorphin [D12.644.400.400.935.119]
        
        alpha-MSH [D12.644.400.400.935.179]
        
        beta-Endorphin [D12.644.400.400.935.239]
        
        beta-Lipotropin [D12.644.400.400.935.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D12.644.400.400.935.498]
        
        gamma-Endorphin [D12.644.400.400.935.505]
        
        gamma-Lipotropin [D12.644.400.400.935.518]
        
        gamma-MSH [D12.644.400.400.935.524]
        
        Melanocortins [D12.644.400.400.935.531]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Neuropeptides [D12.644.400]
    - Hypothalamic Hormones [D12.644.400.400]
      - Pro-Opiomelanocortin [D12.644.400.400.935]
        
        Melanocortins [D12.644.400.400.935.531]
        
        Melanocyte-Stimulating Hormones [D12.644.400.400.935.531.750]
        
        alpha-MSH [D12.644.400.400.935.531.750.050]
        
        beta-MSH [D12.644.400.400.935.531.750.075]
        
        gamma-MSH [D12.644.400.400.935.531.750.115]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Neuropeptides [D12.644.400]
    - Melanocyte-Stimulating Hormones [D12.644.400.460]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Hypothalamic Hormones [D12.644.548.365]
      - Pro-Opiomelanocortin [D12.644.548.365.935]
        
        alpha-Endorphin [D12.644.548.365.935.119]
        
        alpha-MSH [D12.644.548.365.935.179]
        
        beta-Endorphin [D12.644.548.365.935.239]
        
        beta-Lipotropin [D12.644.548.365.935.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D12.644.548.365.935.498]
        
        gamma-Endorphin [D12.644.548.365.935.505]
        
        gamma-Lipotropin [D12.644.548.365.935.518]
        
        gamma-MSH [D12.644.548.365.935.524]
        
        Melanocortins [D12.644.548.365.935.531]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Hypothalamic Hormones [D12.644.548.365]
      - Pro-Opiomelanocortin [D12.644.548.365.935]
        
        Melanocortins [D12.644.548.365.935.531]
        
        Melanocyte-Stimulating Hormones [D12.644.548.365.935.531.750]
        
        alpha-MSH [D12.644.548.365.935.531.750.050]
        
        beta-MSH [D12.644.548.365.935.531.750.075]
        
        gamma-MSH [D12.644.548.365.935.531.750.115]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Pituitary Hormones [D12.644.548.691]
      - Pituitary Hormones, Anterior [D12.644.548.691.525]
        
        Pro-Opiomelanocortin [D12.644.548.691.525.690]
        
        alpha-Endorphin [D12.644.548.691.525.690.119]
        
        alpha-MSH [D12.644.548.691.525.690.179]
        
        beta-Endorphin [D12.644.548.691.525.690.239]
        
        beta-Lipotropin [D12.644.548.691.525.690.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D12.644.548.691.525.690.498]
        
        gamma-Endorphin [D12.644.548.691.525.690.505]
        
        gamma-Lipotropin [D12.644.548.691.525.690.518]
        
        gamma-MSH [D12.644.548.691.525.690.524]
        
        Melanocortins [D12.644.548.691.525.690.531]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Pituitary Hormones [D12.644.548.691]
      - Pituitary Hormones, Anterior [D12.644.548.691.525]
        
        Pro-Opiomelanocortin [D12.644.548.691.525.690]
        
        Melanocortins [D12.644.548.691.525.690.531]
        
        Melanocyte-Stimulating Hormones [D12.644.548.691.525.690.531.750]
        
        alpha-MSH [D12.644.548.691.525.690.531.750.050]
        
        beta-MSH [D12.644.548.691.525.690.531.750.075]
        
        gamma-MSH [D12.644.548.691.525.690.531.750.115]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Neuropeptides [D12.776.631.650]
      - Hypothalamic Hormones [D12.776.631.650.405]
        
        Pro-Opiomelanocortin [D12.776.631.650.405.935]
        
        alpha-Endorphin [D12.776.631.650.405.935.119]
        
        alpha-MSH [D12.776.631.650.405.935.179]
        
        beta-Endorphin [D12.776.631.650.405.935.239]
        
        beta-Lipotropin [D12.776.631.650.405.935.480]
        
        Corticotropin-Like Intermediate Lobe Peptide [D12.776.631.650.405.935.498]
        
        gamma-Endorphin [D12.776.631.650.405.935.505]
        
        gamma-Lipotropin [D12.776.631.650.405.935.518]
        
        gamma-MSH [D12.776.631.650.405.935.524]
        
        Melanocortins [D12.776.631.650.405.935.531]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Neuropeptides [D12.776.631.650]
      - Hypothalamic Hormones [D12.776.631.650.405]
        
        Pro-Opiomelanocortin [D12.776.631.650.405.935]
        
        Melanocortins [D12.776.631.650.405.935.531]
        
        Melanocyte-Stimulating Hormones [D12.776.631.650.405.935.531.750]
        
        alpha-MSH [D12.776.631.650.405.935.531.750.050]
        
        beta-MSH [D12.776.631.650.405.935.531.750.075]
        
        gamma-MSH [D12.776.631.650.405.935.531.750.115]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Neuropeptides [D12.776.631.650]
      - Melanocyte-Stimulating Hormones [D12.776.631.650.460]
        
        alpha-MSH [D12.776.631.650.460.050]
        
        beta-MSH [D12.776.631.650.460.075]
        
        gamma-MSH [D12.776.631.650.460.115]

gamma-MSH Preferred

Concept UI: M0328126
Registry Numbers: 0
Scope Note: An 11-amino acid peptide derived from the N-terminal fragment of pro-opiomelanocortin (POMC). Gamma-MSH stimulates adrenal steroidogenesis and has an regulatory role in the cardiovascular and the renal systems.
Terms: gamma-MSH Preferred Term
Term UI T027099
Date04/24/1981
LexicalTag ACX
ThesaurusID UNK (19XX); gamma-Melanotropin
Term UI T027098
Date01/30/1981
LexicalTag NON
ThesaurusID UNK (19XX); gamma-Melanocyte-Stimulating Hormone
Term UI T365250
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (1998); MSH, gamma
Term UI T365251
Date10/12/1999
LexicalTag ACX
ThesaurusID NLM (1998); Melanocyte-Stimulating Hormone, gamma
Term UI T664032
Date01/10/2006
LexicalTag NON
ThesaurusID NLM (2007)

gamma1-MSH Narrower

gamma2-MSH Narrower

gamma3-MSH Narrower

N-Terminal Peptide of POMC (NPP) Narrower

Concept UI: M0095649
Registry Numbers: 0
Terms: N-Terminal Peptide of POMC (NPP) Preferred Term
Term UI T666187
Date02/13/2006
LexicalTag ACX
ThesaurusID NLM (2007); N-POMC
Term UI T125653
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2007); gamma-Melanotropin Precursor
Term UI T125655
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Pro-gamma-MSH
Term UI T125657
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2007); Pro-gamma-Melanotropin
Term UI T125659
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007)

gamma-MSH MeSH Descriptor Data 2025