MeSH Browser

MeSH Heading: Adrenocorticotropic Hormone
Tree Number(s): D06.472.699.327.935.531.500; D06.472.699.631.525.600.531.500; D12.644.400.400.935.531.500; D12.644.548.365.935.531.500; D12.644.548.691.525.690.531.500; D12.776.631.650.405.935.531.500
Unique ID: D000324
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000324
Scope Note: An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
Entry Term(s): 1-39 ACTH; ACTH; ACTH (1-39); Adrenocorticotrophic Hormone; Adrenocorticotropin; Corticotrophin; Corticotrophin (1-39); Corticotropin; Corticotropin (1-39)
Pharm Action: Hormones
NLM Classification #: WK 515
See Also: Petrosal Sinus Sampling; Receptors, Corticotropin
Public MeSH Note: 2007; see CORTICOTROPIN 1994-2006, see ADRENOCORTICOTROPIC HORMONE 1987-1993, see CORTICOTROPIN 1963-1986
History Note: 2007, 1987-1993 (1963)
Date Established: 2007/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Hypothalamic Hormones [D06.472.699.327]
      - Pro-Opiomelanocortin [D06.472.699.327.935]
        
        Melanocortins [D06.472.699.327.935.531]
        
        Adrenocorticotropic Hormone [D06.472.699.327.935.531.500]
        
        Cosyntropin [D06.472.699.327.935.531.500.200]
        
        Melanocyte-Stimulating Hormones [D06.472.699.327.935.531.750]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]
    - Pituitary Hormones [D06.472.699.631]
      - Pituitary Hormones, Anterior [D06.472.699.631.525]
        
        Pro-Opiomelanocortin [D06.472.699.631.525.600]
        
        Melanocortins [D06.472.699.631.525.600.531]
        
        Adrenocorticotropic Hormone [D06.472.699.631.525.600.531.500]
        
        Cosyntropin [D06.472.699.631.525.600.531.500.200]
        
        Melanocyte-Stimulating Hormones [D06.472.699.631.525.600.531.750]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Neuropeptides [D12.644.400]
    - Hypothalamic Hormones [D12.644.400.400]
      - Pro-Opiomelanocortin [D12.644.400.400.935]
        
        Melanocortins [D12.644.400.400.935.531]
        
        Adrenocorticotropic Hormone [D12.644.400.400.935.531.500]
        
        Cosyntropin [D12.644.400.400.935.531.500.200]
        
        Melanocyte-Stimulating Hormones [D12.644.400.400.935.531.750]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Hypothalamic Hormones [D12.644.548.365]
      - Pro-Opiomelanocortin [D12.644.548.365.935]
        
        Melanocortins [D12.644.548.365.935.531]
        
        Adrenocorticotropic Hormone [D12.644.548.365.935.531.500]
        
        Cosyntropin [D12.644.548.365.935.531.500.200]
        
        Melanocyte-Stimulating Hormones [D12.644.548.365.935.531.750]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]
    - Pituitary Hormones [D12.644.548.691]
      - Pituitary Hormones, Anterior [D12.644.548.691.525]
        
        Pro-Opiomelanocortin [D12.644.548.691.525.690]
        
        Melanocortins [D12.644.548.691.525.690.531]
        
        Adrenocorticotropic Hormone [D12.644.548.691.525.690.531.500]
        
        Cosyntropin [D12.644.548.691.525.690.531.500.200]
        
        Melanocyte-Stimulating Hormones [D12.644.548.691.525.690.531.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Neuropeptides [D12.776.631.650]
      - Hypothalamic Hormones [D12.776.631.650.405]
        
        Pro-Opiomelanocortin [D12.776.631.650.405.935]
        
        Melanocortins [D12.776.631.650.405.935.531]
        
        Adrenocorticotropic Hormone [D12.776.631.650.405.935.531.500]
        
        Cosyntropin [D12.776.631.650.405.935.531.500.200]
        
        Melanocyte-Stimulating Hormones [D12.776.631.650.405.935.531.750]

Adrenocorticotropic Hormone Preferred

Concept UI: M0000499
Scope Note: An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
Terms: Adrenocorticotropic Hormone Preferred Term
Term UI T001063
Date04/19/1993
LexicalTag NON
ThesaurusID NLM (1994); Corticotropin
Term UI T001065
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Corticotropin (1-39)
Term UI T001066
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX); Corticotrophin (1-39)
Term UI T001067
Date03/19/1990
LexicalTag NON
ThesaurusID NLM (1991); Adrenocorticotrophic Hormone
Term UI T001068
Date03/19/1990
LexicalTag NON
ThesaurusID NLM (1991); Adrenocorticotropin
Term UI T001064
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); 1-39 ACTH
Term UI T001060
Date06/25/1981
LexicalTag ABB
ThesaurusID UNK (19XX); ACTH (1-39)
Term UI T001061
Date09/09/1983
LexicalTag ABB
ThesaurusID UNK (19XX); ACTH
Term UI T001062
Date03/29/1974
LexicalTag ABB
ThesaurusID UNK (19XX); Corticotrophin
Term UI T001069
Date03/19/1990
LexicalTag NON
ThesaurusID NLM (1991)

Adrenocorticotropic Hormone MeSH Descriptor Data 2025