MeSH Browser

MeSH Heading: Proglucagon
Tree Number(s): D06.472.317.680; D06.472.699.587.730; D12.644.548.586.730; D12.776.811.700
Unique ID: D052336
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D052336
Scope Note: The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.
Entry Term(s): Glucagon Precursor; Glucagon Precursors; Pre-Proglucagons; Preproglucagon; Preproglucagons; Pro-Glucagon
Previous Indexing: Enteroglucagon (1982-2005); Glucagon (1973-2005)
Public MeSH Note: 2007; see GLUCAGON PRECURSORS 2006; GLUCAGON PRECURSOR was indexed under PROGLUCAGON 2006-2007, PROTEIN PRECURSORS & GLUCAGON 1977-2005
History Note: 2007 (2006); for GLUCAGON PRECURSOR use GLUCAGON PRECURSOR (NM) 1977-2007
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2018/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Proglucagon MeSH Descriptor Data 2025