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Pancreatic Polypeptide MeSH Descriptor Data 2023


MeSH Heading
Pancreatic Polypeptide
Tree Number(s)
D06.472.699.587.700
D12.644.400.600
D12.644.548.586.700
D12.776.631.650.600
Unique ID
D010191
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010191
Scope Note
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Entry Term(s)
Pancreatic Polypeptide (PP)
Pancreatic Polypeptide Hormone
Pancreatic Prohormone
Pharm Action
Gastrointestinal Agents
Hormones
Registry Number
59763-91-6
Previous Indexing
Hormones (1966-1973)
Pancreatic Hormones (1974-1978)
Peptides (1966-1978)
Public MeSH Note
79
History Note
79
Date Established
1979/01/01
Date of Entry
1978/05/18
Revision Date
2015/11/24
Pancreatic Polypeptide Preferred
Pancreatic Prohormone Broader
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