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Somatostatin MeSH Descriptor Data 2022


MeSH Heading
Somatostatin
Tree Number(s)
D06.472.699.327.700.875
D06.472.699.587.780
D12.644.400.400.700.875
D12.644.548.365.700.875
D12.644.548.586.780
D12.776.631.650.405.700.875
Unique ID
D013004
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013004
Scope Note
A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Entry Term(s)
Cyclic Somatostatin
SRIH-14
Somatofalk
Somatostatin, Cyclic
Somatostatin-14
Somatotropin Release-Inhibiting Factor
Somatotropin Release-Inhibiting Hormone
Stilamin
Pharm Action
Hormones
Registry Number
51110-01-1
NLM Classification #
WK 515
Previous Indexing
Somatotropin Releasing Hormone/antagonists & inhibitors (1974)
Somatotropin/antagonists & inhibitors (1973-1974)
See Also
Receptors, Somatostatin
Public MeSH Note
99
Online Note
use SOMATOSTATIN to search SOMATOTROPIN RELEASE INHIBITING HORMONE 1975-84
History Note
99
Date Established
1975/09/01
Date of Entry
1974/11/11
Revision Date
2015/11/24
Somatostatin Preferred
Stilamin Narrower
Somatofalk Narrower
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