MeSH Browser

MeSH Heading: Peptide PHI
Tree Number(s): D06.472.699.592; D12.644.400.610; D12.644.548.592; D12.776.631.650.610
Unique ID: D010451
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010451
Annotation: a neurotransmitter; entry term explains PHI
Scope Note: A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The exact amino acid composition of the peptide is species dependent. The peptide is secreted in the intestine, but is found in the nervous system, many organs, and in the majority of peripheral tissues. It has a wide range of biological actions, affecting the cardiovascular, gastrointestinal, respiratory, and central nervous systems.
Entry Term(s): Human PHI; Neuropeptide PHI 27; PHI Peptide; PHM Neuropeptide; PHM-27; Peptide HI; Peptide Histidine Methionine; Peptide Histidine-Isoleucine; Peptide PHI-27; Peptide PHM; Peptide-Histidine-Isoleucinamide; Porcine Intestinal Heptacosapeptide; Pro-Vasoactive Intestinal Peptide
Previous Indexing: Gastrointestinal Hormones (1966-1986); Peptides (1966-1986)
Public MeSH Note: 87
History Note: 87
Date Established: 1987/01/01
Date of Entry: 1986/04/14
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Peptide Hormones [D06.472.699]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Neuropeptides [D12.644.400]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Peptide Hormones [D12.644.548]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Neuropeptides [D12.776.631.650]

Peptide PHI Preferred

Concept UI: M0016232
Scope Note: A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The exact amino acid composition of the peptide is species dependent. The peptide is secreted in the intestine, but is found in the nervous system, many organs, and in the majority of peripheral tissues. It has a wide range of biological actions, affecting the cardiovascular, gastrointestinal, respiratory, and central nervous systems.
Terms: Peptide PHI Preferred Term
Term UI T030886
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1987); Peptide Histidine-Isoleucine
Term UI T030884
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); PHI Peptide
Term UI T030885
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); Peptide PHI-27
Term UI T030887
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); Peptide PHM
Term UI T030888
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); Peptide-Histidine-Isoleucinamide
Term UI T030889
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX); PHM Neuropeptide
Term UI T030890
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); Pro-Vasoactive Intestinal Peptide
Term UI T030891
Date08/07/1986
LexicalTag NON
ThesaurusID UNK (19XX); PHM-27
Term UI T030892
Date04/14/1986
LexicalTag ABB
ThesaurusID UNK (19XX); Neuropeptide PHI 27
Term UI T030881
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX); Peptide Histidine Methionine
Term UI T030883
Date08/08/1988
LexicalTag NON
ThesaurusID UNK (19XX); Peptide HI
Term UI T030882
Date04/14/1986
LexicalTag NON
ThesaurusID UNK (19XX)

Human PHI Narrower

Porcine Intestinal Heptacosapeptide Narrower

Peptide PHI MeSH Descriptor Data 2025