MeSH Browser

MeSH Heading: Urocortins
Tree Number(s): D06.472.699.857; D12.644.400.837; D12.644.548.887
Unique ID: D054832
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054832
Scope Note: Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
Entry Term(s): Ucn II; Ucn III; Urocortin; Urocortin 1; Urocortin 2; Urocortin 3; Urocortin I; Urocortin II; Urocortin III
Previous Indexing: Corticotropin-Releasing Hormone (1995-2007)
Public MeSH Note: 2008; UROCORTIN was indexed under CORTICOTROPIN-RELEASING HORMONE 1995-2007
History Note: 2008 (1995)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Urocortins MeSH Descriptor Data 2025