MeSH Browser

MeSH Heading: Chromogranins
Tree Number(s): D12.776.631.199; D12.776.811.185
Unique ID: D002864
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002864
Scope Note: A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.
Entry Term(s): Chromogranin; Granin; Granins; Secretogranin; Secretogranins
Previous Indexing: Chromaffin System (1966-1972); Nerve Tissue Proteins (1966-1972)
Public MeSH Note: 1991; see NERVE TISSUE PROTEINS 1973-1990; SECRETOGRANINS was indexed under CHROMOGRANINS 1985-2006
History Note: 1991(1973)
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004395
Scope Note: A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.
Terms: Chromogranins Preferred Term
Term UI T008321
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1973); Secretogranin
Term UI T000997910
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Chromogranin
Term UI T000997911
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Granin
Term UI T000997913
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Secretogranins
Term UI T166122
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Granins
Term UI T642390
Date06/07/2005
LexicalTag NON
ThesaurusID NLM (2007)

Chromogranins MeSH Descriptor Data 2025