MeSH Browser

MeSH Heading: Acid Sensing Ion Channels
Tree Number(s): D12.776.157.530.400.875.050; D12.776.543.550.450.875.050; D12.776.543.585.400.875.050; D12.776.631.024
Unique ID: D062565
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D062565
Scope Note: A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.
Entry Term(s): ASIC Channel; Acid Sensing Ion Channel; Acid-Sensing Ion Channel; Acid-Sensing Ion Channels; Proton-Gated Sodium Channel; Proton-Gated Sodium Channels
Previous Indexing: Sodium Channels (1988-2012)
Public MeSH Note: 2013; ASIC CHANNEL (now ACID SENSING ION CHANNELS) was indexed under NERVE TISSUE PROTEINS and SODIUM CHANNELS 2009-2012, and under MEMBRANE PROTEINS 1997-2008
History Note: 2013
Entry Combination: agonists:Sodium Channel Agonists; antagonists & inhibitors:Acid Sensing Ion Channel Blockers
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2021/06/30

Entry Combination: agonists:Sodium Channel Agonists; antagonists & inhibitors:Acid Sensing Ion Channel Blockers
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0568648
Scope Note: A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.
Terms: Acid Sensing Ion Channels Preferred Term
Term UI T813499
Date12/01/2011
LexicalTag NON
ThesaurusID NLM (2013); Acid Sensing Ion Channel
Term UI T000997728
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Acid-Sensing Ion Channel
Term UI T000997729
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Proton-Gated Sodium Channel
Term UI T000997730
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Acid-Sensing Ion Channels
Term UI T813500
Date12/01/2011
LexicalTag NON
ThesaurusID NLM (2013); ASIC Channel
Term UI T813501
Date12/01/2011
LexicalTag ABX
ThesaurusID NLM (2013); Proton-Gated Sodium Channels
Term UI T814309
Date12/13/2011
LexicalTag NON
ThesaurusID NLM (2013)

Acid Sensing Ion Channels MeSH Descriptor Data 2025