MeSH Browser

MeSH Heading: Dopamine and cAMP-Regulated Phosphoprotein 32
Tree Number(s): D12.776.631.249; D12.776.744.459
Unique ID: D051937
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051937
Scope Note: A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCLASE in the CORPUS STRIATUM. It regulates the activities of PROTEIN PHOSPHATASE-1 and PROTEIN KINASE A, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of DOPAMINE.
Entry Term(s): DARPP-32 Protein; Dopamine and Adenosine 3',5'-Monophosphate-Regulated Phosphoprotein; Dopamine and cAMP-Regulated Phosphoprotein; Dopamine- and Cyclic AMP-Regulated Phosphoprotein Mr 32,000
Public MeSH Note: 2006; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN was indexed under NERVE TISSUE PROTEINS & PHOSPHOPROTEINS 1984-2005
History Note: 2006(1984)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Dopamine and cAMP-Regulated Phosphoprotein 32 MeSH Descriptor Data 2025