MeSH Browser

MeSH Heading: Fanconi Anemia Complementation Group D2 Protein
Tree Number(s): D12.776.313.812; D12.776.660.285; D12.776.744.484
Unique ID: D052236
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D052236
Scope Note: A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
Entry Term(s): FANCD2 Protein; Fanconi Anemia Group D2 Complementing Protein; Fanconi Anemia Group D2 Protein
Public MeSH Note: 2006; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN was indexed under NUCLEAR PROTEINS 2001-2005
History Note: 2006(2001)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Fanconi Anemia Complementation Group D2 Protein MeSH Descriptor Data 2025