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DNA Repair MeSH Descriptor Data 2023


MeSH Heading
DNA Repair
Tree Number(s)
G02.111.222
G05.219
Unique ID
D004260
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004260
Annotation
coord IM with specific DNA (IM)
Scope Note
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Entry Term(s)
Base Excision Repair
Excision Repair
Nucleotide Excision Repair
Previous Indexing
DNA (1966-1970)
DNA/biosynthesis (1966-1970)
See Also
Pyrimidine Dimers
Public MeSH Note
74
History Note
74(71)
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/17
DNA Repair Preferred
Excision Repair Narrower
Nucleotide Excision Repair Narrower
Base Excision Repair Narrower
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