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DNA Repair MeSH Descriptor Data 2023

MeSH Heading
DNA Repair
Tree Number(s)
Unique ID
RDF Unique Identifier
coord IM with specific DNA (IM)
Scope Note
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Entry Term(s)
Base Excision Repair
Excision Repair
Nucleotide Excision Repair
Previous Indexing
DNA (1966-1970)
DNA/biosynthesis (1966-1970)
See Also
Pyrimidine Dimers
Public MeSH Note
History Note
Date Established
Date of Entry
Revision Date
DNA Repair Preferred
Excision Repair Narrower
Nucleotide Excision Repair Narrower
Base Excision Repair Narrower
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