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Melanogenesis MeSH Descriptor Data 2025


MeSH Heading
Melanogenesis
Tree Number(s)
G02.111.545
G03.474
G04.536
Unique ID
D000095868
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000095868
Annotation
animal only: for human, use MELANIN/ biosyn
Scope Note
The biosynthesis of MELANINS in insects and higher animals. The key chemical step of melanogenesis is the initial conversion of TYROSINE to DOPAQUINONE by TYROSINASE, distinguishing melanogenesis from pathways for melanin synthesis in plants. Melanogenesis is complex process involving several stages from the formation of MELANOCYTES during EMBRYONIC DEVELOPMENT to the synthesis of MELANINS in the MELANOSOMES and their distribution via transport of the melanosomes to surrounding KERATINOCYTES.
Entry Term(s)
Eumelanogenesis
Phaeomelanogenesis
Previous Indexing
Melanins/metabolism (1963-2023)
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/12
Melanogenesis Preferred
Eumelanogenesis Narrower
Phaeomelanogenesis Narrower
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