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Down-Regulation MeSH Descriptor Data 2023


MeSH Heading
Down-Regulation
Tree Number(s)
G02.111.240
G05.308.200
G07.690.773.937
Unique ID
D015536
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015536
Scope Note
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Entry Term(s)
Down-Regulation (Physiology)
Downregulation
Receptor Down-Regulation
See Also
Feedback, Physiological
Up-Regulation
Public MeSH Note
2002; see Down-Regulation (Physiology) 1990-2001
History Note
2002 (1990)
Date Established
1990/01/01
Date of Entry
1989/05/26
Revision Date
2016/06/17
Down-Regulation Preferred
Receptor Down-Regulation Narrower
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