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Drug Tolerance MeSH Descriptor Data 2026


MeSH Heading
Drug Tolerance
Tree Number(s)
G07.690.773.992
Unique ID
D004361
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004361
Annotation
differentiate from DRUG RESISTANCE; not for tolerability ( = drug /‌adv eff): Manual 28.19
Scope Note
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
NLM Classification #
QV 37
Date Introduced
1966/01/01
Last Updated
2015/06/29
Drug Tolerance Preferred
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