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No-Observed-Adverse-Effect Level
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
No-Observed-Adverse-Effect Level
Tree Number(s)
E05.940.600
G07.690.936.750
Unique ID
D019055
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019055
Annotation
coordinate NIM with specific drug / tox (IM)
Scope Note
The highest dosage administered that does not produce toxic effects.
Entry Version
NO OBSERVED ADV EFF LEVEL
Entry Term(s)
Acceptable Daily Intake
NOAEL
No-Observed-Effect Level
Tolerable Daily Intake
Previous Indexing
specific drug /toxicity (1983-1995)
Public MeSH Note
96
History Note
96
Date Established
1996/01/01
Date of Entry
1995/05/26
Revision Date
2015/06/29
No Qualifiers
Investigative Techniques [E05]
Toxicity Tests [E05.940]
Carcinogenicity Tests [E05.940.150]
Cytotoxicity Tests, Immunologic [E05.940.245]
Inhibitory Concentration 50 [E05.940.350]
Lethal Dose 50 [E05.940.402]
Maximum Tolerated Dose [E05.940.481]
Mutagenicity Tests [E05.940.560]
No-Observed-Adverse-Effect Level [E05.940.600]
Toxicity Tests, Acute [E05.940.790]
Toxicity Tests, Chronic [E05.940.800]
Toxicity Tests, Subacute [E05.940.850]
Toxicity Tests, Subchronic [E05.940.900]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Toxicological Phenomena [G07.690.936]
Dose-Response Relationship, Drug [G07.690.936.500]
Inhibitory Concentration 50 [G07.690.936.563]
Maximum Tolerated Dose [G07.690.936.625]
No-Observed-Adverse-Effect Level [G07.690.936.750]
Expand All
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No-Observed-Adverse-Effect Level
Preferred
Concept UI
M0028446
Scope Note
The highest dosage administered that does not produce toxic effects.
Terms
No-Observed-Adverse-Effect Level
Preferred Term
Term UI
T056906
Date
01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1996)
NOAEL
Term UI
T056907
Date
02/02/1995
LexicalTag
ABB
ThesaurusID
NLM (1996)
No-Observed-Effect Level
Broader
Concept UI
M0028445
Terms
No-Observed-Effect Level
Preferred Term
Term UI
T056904
Date
02/02/1995
LexicalTag
NON
ThesaurusID
NLM (1996)
Acceptable Daily Intake
Related
Concept UI
M0580040
Scope Note
The daily amount of chemical that can be ingested, which during an entire lifetime appears to be without appreciable health risk. The acceptable daily intake values can be calculated from
NO-OBSERVED-ADVERSE-EFFECT LEVEL
values.
Terms
Acceptable Daily Intake
Preferred Term
Term UI
T835128
Date
01/03/2013
LexicalTag
NON
ThesaurusID
NLM (2014)
Tolerable Daily Intake
Term UI
T835129
Date
01/03/2013
LexicalTag
NON
ThesaurusID
NLM (2014)
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