NLM Logo

Nucleic Acid Hybridization MeSH Descriptor Data 2023


MeSH Heading
Nucleic Acid Hybridization
Tree Number(s)
E05.393.661
G02.111.611
Unique ID
D009693
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009693
Annotation
IM general only; coord NIM with DNA or RNA or specific (IM); IN SITU HYBRIDIZATION & IN SITU HYBRIDIZATION, FLUORESCENCE are available
Scope Note
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Entry Term(s)
Genomic Hybridization
NLM Classification #
QU 58
Previous Indexing
DNA (1966-1970)
RNA (1966-1970)
See Also
Blotting, Southern
Public MeSH Note
72
History Note
72(71)
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/17
Nucleic Acid Hybridization Preferred
Genomic Hybridization Broader
page delivered in 0.222s