Technique in which endogenous ENVELOPE PROTEINS have been replaced by use of a chimeric vector. For instance a viral vector with SIMIAN IMMUNODEFICIENCY VIRUS can be coated with the VIRAL ENVELOPE PROTEINS from Vesicular stomatitus virus. Use of these types of vectors are useful in developing NEUTRALIZATION TESTS by enabling infection of almost universal set of host cells.
Technique in which endogenous ENVELOPE PROTEINS have been replaced by use of a chimeric vector. For instance a viral vector with SIMIAN IMMUNODEFICIENCY VIRUS can be coated with the VIRAL ENVELOPE PROTEINS from Vesicular stomatitus virus. Use of these types of vectors are useful in developing NEUTRALIZATION TESTS by enabling infection of almost universal set of host cells.
Process by which different classes of viruses enter the host cell wherein the VIRAL GENOME or VIRION slips through the host membrane by attaching to entry proteins of another class of virus.
