MeSH Browser

MeSH Heading: DNA Damage Tolerance
Tree Number(s): G02.111.225.380; G05.226.380
Unique ID: D000097122
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097122
Scope Note: Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.
Entry Term(s): DNA Damage Bypass Pathways; DNA Damage Tolerance Pathways; DNA Damage Tolerant Replication; Post Replication Repair; Post-Replication Repair; Postreplication Repair; Postreplicative Repair; Postreplicative Template Switching; Replication Fork Reversal; Replication Template Switching
See Also: DNA Repair
Public MeSH Note: 2024
History Note: 2024
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/26

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000763247
Scope Note: Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.
Terms: DNA Damage Tolerance Preferred Term
Term UI T001134081
Date03/02/2023
LexicalTag NON
ThesaurusID NLM (2024); Post Replication Repair
Term UI T001134349
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); Postreplicative Repair
Term UI T001134350
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); DNA Damage Tolerant Replication
Term UI T001134351
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); DNA Damage Tolerance Pathways
Term UI T001134355
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); Postreplication Repair
Term UI T001134346
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); Post-Replication Repair
Term UI T001134348
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024); DNA Damage Bypass Pathways
Term UI T001134356
Date03/03/2023
LexicalTag NON
ThesaurusID NLM (2024)

DNA Damage Tolerance MeSH Descriptor Data 2025