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MeSH 2024
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Genomic Instability
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Genomic Instability
Tree Number(s)
C23.550.362
G05.365.590.335
G05.370
Unique ID
D042822
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D042822
Scope Note
An increased tendency of the
GENOME
to acquire
MUTATIONS
when various processes involved in maintaining and replicating the genome are dysfunctional.
Entry Term(s)
Genome Instability
Genome Stability
Genomic Stability
See Also
Chromothripsis
DNA Sequence, Unstable
Public MeSH Note
2004
History Note
2004
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2016/07/05
Allowable Qualifiers
drug effects (DE)
ethics (ES)
genetics (GE)
immunology (IM)
physiology (PH)
radiation effects (RE)
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Acantholysis [C23.550.035]
Arrhythmias, Cardiac [C23.550.073]
Ascites [C23.550.081]
Atrial Remodeling [C23.550.113]
Azotemia [C23.550.145]
Cardiotoxicity [C23.550.161]
Channelopathies [C23.550.177]
Chromosome Aberrations [C23.550.210]
Death [C23.550.260]
Dehydration [C23.550.274]
Delayed Graft Function [C23.550.277]
Disease [C23.550.288]
Disease Attributes [C23.550.291]
Dysbiosis [C23.550.308]
Emphysema [C23.550.325]
Extravasation of Diagnostic and Therapeutic Materials [C23.550.340]
Femoracetabular Impingement [C23.550.347]
Fibrosis [C23.550.355]
Frailty [C23.550.359]
Genomic Instability [C23.550.362]
Chromosomal Instability [C23.550.362.180]
Microsatellite Instability [C23.550.362.590]
Gliosis [C23.550.369]
Granuloma [C23.550.382]
Granulomatosis, Orofacial [C23.550.384]
Growth Disorders [C23.550.393]
Hemolysis [C23.550.403]
Hemorrhage [C23.550.414]
Hyperammonemia [C23.550.421]
Hyperamylasemia [C23.550.425]
Hyperbilirubinemia [C23.550.429]
Hyperplasia [C23.550.444]
Hyperuricemia [C23.550.449]
Hypovolemia [C23.550.455]
Inflammation [C23.550.470]
Intraoperative Complications [C23.550.505]
Ischemia [C23.550.513]
Leukoaraiosis [C23.550.522]
Leukocytosis [C23.550.526]
Lithiasis [C23.550.537]
Long Term Adverse Effects [C23.550.543]
Malacoplakia [C23.550.548]
Menstruation Disturbances [C23.550.568]
Metaplasia [C23.550.589]
Muscle Weakness [C23.550.695]
Myotoxicity [C23.550.706]
Necrosis [C23.550.717]
Neointima [C23.550.722]
Neoplastic Processes [C23.550.727]
Nerve Degeneration [C23.550.737]
Ochronosis [C23.550.744]
Ossification, Heterotopic [C23.550.751]
Ototoxicity [C23.550.753]
Pigmentation Disorders [C23.550.755]
Polydipsia [C23.550.759]
Postoperative Complications [C23.550.767]
Protein Aggregation, Pathological [C23.550.770]
Respiratory Aspiration [C23.550.773]
Retropneumoperitoneum [C23.550.794]
Sclerosis [C23.550.823]
Shock [C23.550.835]
Teratogenesis [C23.550.863]
Toxic Optic Neuropathy [C23.550.877]
Ulcer [C23.550.891]
Vascular Remodeling [C23.550.918]
Yang Deficiency [C23.550.945]
Yin Deficiency [C23.550.972]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]
Allelic Imbalance [G05.365.590.029]
Base Pair Mismatch [G05.365.590.060]
Chromosome Aberrations [G05.365.590.175]
Codon, Nonsense [G05.365.590.195]
DNA Repeat Expansion [G05.365.590.220]
Frameshift Mutation [G05.365.590.265]
Gain of Function Mutation [G05.365.590.288]
Gene Amplification [G05.365.590.310]
Gene Duplication [G05.365.590.320]
Genomic Instability [G05.365.590.335]
Microsatellite Instability [G05.365.590.335.590]
Germ-Line Mutation [G05.365.590.350]
INDEL Mutation [G05.365.590.500]
Loss of Function Mutation [G05.365.590.538]
Mutagenesis, Insertional [G05.365.590.575]
Mutation Accumulation [G05.365.590.594]
Mutation Rate [G05.365.590.612]
Mutation, Missense [G05.365.590.650]
Point Mutation [G05.365.590.675]
Sequence Deletion [G05.365.590.762]
Sequence Inversion [G05.365.590.770]
Silent Mutation [G05.365.590.803]
Suppression, Genetic [G05.365.590.835]
Synthetic Lethal Mutations [G05.365.590.917]
Genetic Phenomena [G05]
Biological Evolution [G05.045]
Breeding [G05.090]
Cell Division [G05.113]
Cellular Reprogramming [G05.135]
Clonal Evolution [G05.158]
Consanguinity [G05.180]
DNA Cleavage [G05.193]
DNA Damage [G05.200]
DNA Methylation [G05.206]
DNA Packaging [G05.213]
DNA Repair [G05.219]
DNA Replication [G05.226]
DNA Transformation Competence [G05.232]
Founder Effect [G05.285]
Gene Expression [G05.297]
Gene Expression Regulation [G05.308]
Gene Frequency [G05.330]
Gene Order [G05.340]
Gene Pool [G05.342]
Gene Rearrangement [G05.344]
Genetic Background [G05.346]
Genetic Fitness [G05.347]
Genetic Linkage [G05.348]
Genetic Load [G05.350]
Genetic Structures [G05.360]
Genetic Variation [G05.365]
Genomic Instability [G05.370]
Chromosomal Instability [G05.370.180]
Microsatellite Instability [G05.370.590]
Genotype [G05.380]
Heredity [G05.390]
Hybrid Vigor [G05.400]
Inbreeding Depression [G05.410]
Inheritance Patterns [G05.420]
Molecular Mimicry [G05.545]
Mutagenesis [G05.558]
Nucleic Acid Denaturation [G05.627]
Phenotype [G05.695]
Ploidies [G05.700]
Recombination, Genetic [G05.728]
RNA Cleavage [G05.755]
RNA Damage [G05.762]
RNA Replication [G05.769]
Selection, Genetic [G05.783]
Sequence Homology [G05.810]
Sex Determination Processes [G05.813]
Sex Ratio [G05.815]
Structural Homology, Protein [G05.820]
Sympatry [G05.910]
Virus Integration [G05.935]
Expand All
Collapse All
Genomic Instability
Preferred
Concept UI
M0442085
Scope Note
An increased tendency of the
GENOME
to acquire
MUTATIONS
when various processes involved in maintaining and replicating the genome are dysfunctional.
Terms
Genomic Instability
Preferred Term
Term UI
T526127
Date
11/14/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
Genome Instability
Term UI
T526128
Date
11/14/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
Genomic Stability
Related
Concept UI
M0443450
Terms
Genomic Stability
Preferred Term
Term UI
T528257
Date
12/13/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
Genome Stability
Term UI
T528258
Date
12/13/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
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