MeSH Browser

MeSH Heading: Germ-Line Mutation
Tree Number(s): G05.365.590.350
Unique ID: D018095
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018095
Annotation: germ-line refers to germ cells (ovum or spermatozoon), not micro-organisms
Scope Note: Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., generative cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not.
Entry Term(s): Germline Mutation; Mutation, Germ-Line
Previous Indexing: Mutation (1980-1993)
Public MeSH Note: 94
History Note: 94
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Germ-Line Mutation MeSH Descriptor Data 2025