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Germ-Line Mutation MeSH Descriptor Data 2026


MeSH Heading
Germ-Line Mutation
Tree Number(s)
G05.365.590.350
Unique ID
D018095
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018095
Annotation
germ-line refers to germ cells (ovum or spermatozoon), not micro-organisms
Scope Note
Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., generative cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not.
Entry Term(s)
Germline Mutation
Mutation, Germ-Line
Previous Indexing
Mutation (1980-1993)
Public MeSH Note
94
History Note
94
Date Introduced
1994/01/01
Last Updated
2008/07/08
Germ-Line Mutation Preferred
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