MeSH Browser

MeSH Heading: DNA Sequence, Unstable
Tree Number(s): G05.360.340.024.189
Unique ID: D043243
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043243
Scope Note: A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Entry Version: DNA SEQ UNSTABLE
Entry Term(s): Unstable DNA Sequence; Unstable DNA Sequences
See Also: Chromosome Fragility; Genomic Instability
Public MeSH Note: 2004; see TRINUCLEOTIDE REPEAT EXPANSION 1999-2003
History Note: 2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2019/07/01

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

DNA Sequence, Unstable MeSH Descriptor Data 2025