MeSH Browser

MeSH Heading: Inhibitor of Growth Protein 1
Tree Number(s): D12.644.360.368; D12.776.476.383; D12.776.624.776.503; D12.776.660.494
Unique ID: D000076023
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076023
Scope Note: A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
Entry Term(s): ING-1 Protein; ING1 Protein; p33ING Protein
Previous Indexing: Intracellular Signaling Peptides and Proteins (2005-2017); Nuclear Proteins (2005-2017); Tumor Suppressor Proteins (2005-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000631818
Scope Note: A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
Terms: Inhibitor of Growth Protein 1 Preferred Term
Term UI T000924852
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (2018); ING-1 Protein
Term UI T000924854
Date05/18/2017
LexicalTag ABX
ThesaurusID NLM (2018); p33ING Protein
Term UI T000924855
Date05/18/2017
LexicalTag ABX
ThesaurusID NLM (2018); ING1 Protein
Term UI T000924853
Date05/18/2017
LexicalTag ABX
ThesaurusID NLM (2018)

Inhibitor of Growth Protein 1 MeSH Descriptor Data 2025