MeSH Browser

MeSH Heading: Scaffold Protein ILK
Tree Number(s): D12.644.360.757; D12.776.476.750
Unique ID: D000099200
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099200
Scope Note: A scaffold protein originally thought to function as a SERINE-THREONINE PROTEIN KINASE. It lacks kinase activity and regulates a variety of cellular processes that include CELL ADHESION; CELL MIGRATION; and assembly of FOCAL ADHESIONS.
Entry Term(s): ILK Kinase; ILK-2 Kinase; Integrin-linked Kinase; Integrin-linked Kinase 2; p59 ILK; p59(ILK)
Public MeSH Note: 2026; see INTEGRIN-LINKED KINASE (NM) 1996-2026; INTEGRIN-LINKED KINASE was indexed under PROTEIN SERINE-THREONINE KINASES 1996-2026
History Note: 2026 (1996); use INTEGRIN-LINKED KINASE (NM) 1996-2026
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000768920
Scope Note: A scaffold protein originally thought to function as a SERINE-THREONINE PROTEIN KINASE. It lacks kinase activity and regulates a variety of cellular processes that include CELL ADHESION; CELL MIGRATION; and assembly of FOCAL ADHESIONS.
Terms: Scaffold Protein ILK Preferred Term
Term UI T001147941
Date04/09/2025
LexicalTag ABX
ThesaurusID NLM (2026); ILK Kinase
Term UI T001148016
Date04/10/2025
LexicalTag ABX
ThesaurusID NLM (2026); ILK-2 Kinase
Term UI T001147942
Date04/09/2025
LexicalTag ABX
ThesaurusID NLM (2007); Integrin-linked Kinase
Term UI T001147943
Date04/09/2025
LexicalTag NON
ThesaurusID NLM (1996); Integrin-linked Kinase 2
Term UI T001147944
Date04/09/2025
LexicalTag NON
ThesaurusID NLM (2007); p59 ILK
Term UI T286290
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (1996); p59(ILK)
Term UI T286291
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (1996)

Scaffold Protein ILK MeSH Descriptor Data 2026