Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
Protein Tyrosine Phosphatases MeSH Descriptor Data 2026
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Entry Term(s)
PTPase
Phosphotyrosine Phosphatase
Phosphotyrosyl Protein Phosphatase
Protein-Tyrosine Phosphatase
Protein-Tyrosine-Phosphatase
Tyrosyl Phosphoprotein Phosphatase
Registry Numbers
EC 3.1.3.48
Related Numbers
79747-53-8
CAS Type 1 Name
Protein-tyrosine-phosphate phosphohydrolase
Previous Indexing
Phosphoprotein Phosphatases (1985-1991)
Public MeSH Note
2008; see PROTEIN-TYROSINE-PHOSPHATASE 1992-2007; PROTEIN-TYROSINE PHOSPHATASE was indexed under PHOSPHOPROTEIN PHOSPHATASES 1985-1991
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.