Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Protein Tyrosine Phosphatases MeSH Descriptor Data 2026


MeSH Heading
Protein Tyrosine Phosphatases
Tree Number(s)
D08.811.277.352.650.775
D12.776.476.564
Unique ID
D017027
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017027
Annotation
general; prefer specifics
Scope Note
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Entry Term(s)
PTPase
Phosphotyrosine Phosphatase
Phosphotyrosyl Protein Phosphatase
Protein-Tyrosine Phosphatase
Protein-Tyrosine-Phosphatase
Tyrosyl Phosphoprotein Phosphatase
Registry Numbers
EC 3.1.3.48
Related Numbers
79747-53-8
CAS Type 1 Name
Protein-tyrosine-phosphate phosphohydrolase
Previous Indexing
Phosphoprotein Phosphatases (1985-1991)
Public MeSH Note
2008; see PROTEIN-TYROSINE-PHOSPHATASE 1992-2007; PROTEIN-TYROSINE PHOSPHATASE was indexed under PHOSPHOPROTEIN PHOSPHATASES 1985-1991
History Note
2008(1985)
Date Introduced
1992/01/01
Last Updated
2021/05/21
Protein Tyrosine Phosphatases Preferred
page delivered in 0.177s