MeSH Browser

MeSH Heading: Tumor Necrosis Factor alpha-Induced Protein 3
Tree Number(s): D08.811.037.750.500; D08.811.277.656.300.887.750; D08.811.464.938.750.813; D12.644.360.950; D12.776.476.938
Unique ID: D000072598
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072598
Scope Note: A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.
Entry Term(s): TNFAIP3 Protein; Zinc Finger Protein A20
Registry Numbers: EC 3.4.19.12
Previous Indexing: Cysteine Endopeptidases (2006-2016); DNA-Binding Proteins (2006-2016); Intracellular Signaling Peptides and Proteins (2006-2016); Nuclear Proteins (1992-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000617434
Registry Numbers: EC 3.4.19.12
Scope Note: A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.
Terms: Tumor Necrosis Factor alpha-Induced Protein 3 Preferred Term
Term UI T000900278
Date05/02/2016
LexicalTag NON
ThesaurusID NLM (2017); TNFAIP3 Protein
Term UI T000900280
Date05/02/2016
LexicalTag ABX
ThesaurusID NLM (2017); Zinc Finger Protein A20
Term UI T000900281
Date05/02/2016
LexicalTag NON
ThesaurusID NLM (2017)

Tumor Necrosis Factor alpha-Induced Protein 3 MeSH Descriptor Data 2025