MeSH Browser

MeSH Heading: Deubiquitinating Enzymes
Tree Number(s): D08.811.277.656.281
Unique ID: D000072017
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072017
Scope Note: Enzymes that remove UBIQUITIN from protein substrates, including POLYUBIQUITIN, or from other molecules. They are generally classified under the specific enzyme subclasses such as CYSTEINE PROTEASES, and METALLOPROTEASES.
Entry Term(s): Deubiquitinase; Deubiquitinases; Deubiquitinating Enzyme
Registry Numbers: EC 3.4.19.12
Previous Indexing: Endopeptidases (1997-2016); Ubiquitin (1997-2016); Ubiquitin-Specific Proteases (2014-2016)
Public MeSH Note: 2017
History Note: 2017
Date Introduced: 2017/01/01
Last Updated: 2027/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000616241
Registry Numbers: EC 3.4.19.12
Scope Note: Enzymes that remove UBIQUITIN from protein substrates, including POLYUBIQUITIN, or from other molecules. They are generally classified under the specific enzyme subclasses such as CYSTEINE PROTEASES, and METALLOPROTEASES.
Terms: Deubiquitinating Enzymes Preferred Term
Term UI T000897872
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); Deubiquitinase
Term UI T000996311
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Deubiquitinases
Term UI T000897874
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); Deubiquitinating Enzyme
Term UI T000996450
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021)

Deubiquitinating Enzymes MeSH Descriptor Data 2027