MeSH Browser

MeSH Heading: RNA, Catalytic
Tree Number(s): D08.811.797; D13.444.735.790.199
Unique ID: D016337
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016337
Scope Note: RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
Entry Term(s): Catalytic RNA; Ribozyme; Ribozymes
NLM Classification #: QU 58.7
Previous Indexing: RNA, Ribosomal (1986-1990); RNA Splicing (1986-1990)
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024970
Scope Note: RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
Terms: RNA, Catalytic Preferred Term
Term UI T048764
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1991); Ribozyme
Term UI T000996441
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Ribozymes
Term UI T048763
Date05/02/1990
LexicalTag NON
ThesaurusID NLM (1991); Catalytic RNA
Term UI T645652
Date07/13/2005
LexicalTag ACX
ThesaurusID NLM (2006)

RNA, Catalytic MeSH Descriptor Data 2025