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DNA Restriction-Modification Enzymes MeSH Descriptor Data 2023


MeSH Heading
DNA Restriction-Modification Enzymes
Tree Number(s)
D08.811.150
Unique ID
D015280
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015280
Scope Note
Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Entry Version
RESTRICT MOD ENZYMES
Entry Term(s)
DNA Restriction Modification Enzyme
DNA Restriction Modification Enzymes
DNA Restriction-Modification Enzyme
Restriction Modification System
Restriction Modification Systems
Restriction-Modification System
Restriction-Modification Systems
Registry Number
0
Previous Indexing
DNA Restriction Enzymes (1975-1988)
Methyltransferases (1971-1988)
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/05/23
Revision Date
2020/05/27
DNA Restriction-Modification Enzymes Preferred
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