MeSH Browser

MeSH Heading: Ataxin-3
Tree Number(s): D08.811.037.250; D12.776.631.069.875; D12.776.660.075.875
Unique ID: D000067699
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000067699
Scope Note: A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).
Entry Term(s): ATXN3 Protein; Ataxin-3 Protein; Machado-Joseph Disease Protein; SCA3 Protein; Spinocerebellar Ataxia 3 Protein
Registry Number: EC 3.4.19.12
Previous Indexing: Nerve Tissue Proteins (1998-2015); Nuclear Proteins (1998-2015); Proteins (1995-1997)
See Also: Spinocerebellar Ataxias
Public MeSH Note: 2016; ATAXIN-3 was indexed under NERVE TISSUE PROTEINS AND NUCLEAR PROTEINS 1998-2015, and under PROTEINS 1995-1997
History Note: 2016 (1995)
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000600684
Registry Number: EC 3.4.19.12
Scope Note: A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).
Terms: Ataxin-3 Preferred Term
Term UI T000872358
Date12/17/2014
LexicalTag NON
ThesaurusID NLM (2016); SCA3 Protein
Term UI T000874504
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); Ataxin-3 Protein
Term UI T000874502
Date01/30/2015
LexicalTag NON
ThesaurusID NLM (2016); Machado-Joseph Disease Protein
Term UI T000874503
Date01/30/2015
LexicalTag NON
ThesaurusID NLM (2016); Spinocerebellar Ataxia 3 Protein
Term UI T000873999
Date01/21/2015
LexicalTag NON
ThesaurusID NLM (2016); ATXN3 Protein
Term UI T000874501
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016)

Ataxin-3 MeSH Descriptor Data 2023