MeSH Browser

MeSH Heading: Ubiquitin-Specific Proteases
Tree Number(s): D08.811.037.750; D08.811.277.656.300.887
Unique ID: D064570
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064570
Scope Note: Members of the peptidase C19 family which regulate signal transduction by removing UBIQUITIN from specific protein substrates via a process known as deubiquitination or deubiquitylation.
Entry Term(s): Ubiquitin-Specific Peptidase; Ubiquitin-Specific Peptidases; Ubiquitin-Specific Protease; Ubiquitin-Specific Protease Family
Registry Numbers: EC 3.4.19.12
Public MeSH Note: 2014; UBIQUITIN-SPECIFIC PROTEASES was indexed under ENDOPEPTIDASES 1998-2013
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0582452
Registry Numbers: EC 3.4.19.12
Scope Note: Members of the peptidase C19 family which regulate signal transduction by removing UBIQUITIN from specific protein substrates via a process known as deubiquitination or deubiquitylation.
Terms: Ubiquitin-Specific Proteases Preferred Term
Term UI T840558
Date04/16/2013
LexicalTag NON
ThesaurusID NLM (2014); Ubiquitin-Specific Protease
Term UI T001010410
Date03/17/2020
LexicalTag NON
ThesaurusID NLM (2021); Ubiquitin-Specific Protease Family
Term UI T000925309
Date05/24/2017
LexicalTag NON
ThesaurusID NLM (2018); Ubiquitin-Specific Peptidases
Term UI T000925282
Date05/24/2017
LexicalTag NON
ThesaurusID NLM (2018); Ubiquitin-Specific Peptidase
Term UI T001010412
Date03/17/2020
LexicalTag NON
ThesaurusID NLM (2021)

Ubiquitin-Specific Proteases MeSH Descriptor Data 2025