ATP-Dependent Endopeptidases MeSH Descriptor Data 2025

MeSH Heading: ATP-Dependent Endopeptidases
Tree Number(s): D08.811.277.040.013.500.032.099; D08.811.277.040.025.024.032.099; D08.811.277.656.149.099; D08.811.277.656.300.065; D12.776.157.025.750.032.099
Unique ID: D057065
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D057065
Scope Note: Endoproteases that contain proteolytic core domains and ATPase-containing regulatory domains.
Entry Term(s): ATP-Dependent Endoprotease; ATP-Dependent Endoproteases; Endoprotease, ATP-Dependent
Previous Indexing: ATP-Dependent Proteases (1981-2009)
Public MeSH Note: 2010; see ATP-DEPENDENT PROTEASES 2005-2009
History Note: 2010; use ATP-DEPENDENT PROTEASES 2005-2009
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - AAA Proteins [D08.811.277.040.013]
        
        ATPases Associated with Diverse Cellular Activities [D08.811.277.040.013.500]
        
        ATP-Dependent Proteases [D08.811.277.040.013.500.032]
        
        ATP-Dependent Endopeptidases [D08.811.277.040.013.500.032.099]
        
        Endopeptidase Clp [D08.811.277.040.013.500.032.099.500]
        
        Protease La [D08.811.277.040.013.500.032.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - Adenosine Triphosphatases [D08.811.277.040.025]
        
        ATPases Associated with Diverse Cellular Activities [D08.811.277.040.025.024]
        
        ATP-Dependent Proteases [D08.811.277.040.025.024.032]
        
        ATP-Dependent Endopeptidases [D08.811.277.040.025.024.032.099]
        
        Endopeptidase Clp [D08.811.277.040.025.024.032.099.500]
        
        Protease La [D08.811.277.040.025.024.032.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - ATP-Dependent Proteases [D08.811.277.656.149]
        
        ATP-Dependent Endopeptidases [D08.811.277.656.149.099]
        
        Endopeptidase Clp [D08.811.277.656.149.099.500]
        
        Protease La [D08.811.277.656.149.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Amyloid Precursor Protein Secretases [D08.811.277.656.300.032]
        
        Aspartic Acid Endopeptidases [D08.811.277.656.300.048]
        
        ATP-Dependent Endopeptidases [D08.811.277.656.300.065]
        
        Endopeptidase Clp [D08.811.277.656.300.065.500]
        
        Protease La [D08.811.277.656.300.065.750]
        
        Brinolase [D08.811.277.656.300.099]
        
        Coagulase [D08.811.277.656.300.174]
        
        Cysteine Endopeptidases [D08.811.277.656.300.200]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Serine Endopeptidases [D08.811.277.656.300.760]
        
        Streptokinase [D08.811.277.656.300.775]
        
        Ubiquitin-Specific Proteases [D08.811.277.656.300.887]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - AAA Proteins [D12.776.157.025]
      - ATPases Associated with Diverse Cellular Activities [D12.776.157.025.750]
        
        ATP-Dependent Proteases [D12.776.157.025.750.032]
        
        ATP-Dependent Endopeptidases [D12.776.157.025.750.032.099]
        
        Endopeptidase Clp [D12.776.157.025.750.032.099.500]
        
        Protease La [D12.776.157.025.750.032.099.750]

ATP-Dependent Endopeptidases Preferred

Concept UI: M0095032
Scope Note: Endoproteases that contain proteolytic core domains and ATPase-containing regulatory domains.
Terms: ATP-Dependent Endopeptidases Preferred Term
Term UI T748379
Date03/30/2009
LexicalTag ABX
ThesaurusID NLM (2010); ATP-Dependent Endoprotease
Term UI T125035
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); Endoprotease, ATP-Dependent
Term UI T125045
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); ATP-Dependent Endoproteases
Term UI T748375
Date03/30/2009
LexicalTag ABX
ThesaurusID NLM (2010)

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