MeSH Browser

MeSH Heading: Metalloendopeptidases
Tree Number(s): D08.811.277.656.300.480; D08.811.277.656.675.374
Unique ID: D008666
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008666
Scope Note: ENDOPEPTIDASES which use a metal such as ZINC in the catalytic mechanism.
Entry Term(s): Metallo-Endoproteinases; Metalloendopeptidase
NLM Classification #: QU 136
Previous Indexing: Peptide Peptidohydrolases (1966-1987)
Public MeSH Note: 2000; see METALLOPROTEINASES 1988-1999
History Note: 2000(1988)
Date Established: 1988/01/01
Date of Entry: 1987/05/04
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Amyloid Precursor Protein Secretases [D08.811.277.656.300.032]
        
        Aspartic Acid Endopeptidases [D08.811.277.656.300.048]
        
        ATP-Dependent Endopeptidases [D08.811.277.656.300.065]
        
        Brinolase [D08.811.277.656.300.099]
        
        Coagulase [D08.811.277.656.300.174]
        
        Cysteine Endopeptidases [D08.811.277.656.300.200]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Botulinum Toxins [D08.811.277.656.300.480.153]
        
        Collagenases [D08.811.277.656.300.480.205]
        
        Endothelin-Converting Enzymes [D08.811.277.656.300.480.229]
        
        Gelatinases [D08.811.277.656.300.480.252]
        
        Insulysin [D08.811.277.656.300.480.300]
        
        Lysostaphin [D08.811.277.656.300.480.452]
        
        Matrix Metalloproteinases [D08.811.277.656.300.480.525]
        
        Mitochondrial Processing Peptidase [D08.811.277.656.300.480.563]
        
        Neprilysin [D08.811.277.656.300.480.600]
        
        PHEX Phosphate Regulating Neutral Endopeptidase [D08.811.277.656.300.480.616]
        
        Pregnancy-Associated Plasma Protein-A [D08.811.277.656.300.480.632]
        
        Procollagen N-Endopeptidase [D08.811.277.656.300.480.664]
        
        Pronase [D08.811.277.656.300.480.680]
        
        Thermolysin [D08.811.277.656.300.480.827]
        
        Serine Endopeptidases [D08.811.277.656.300.760]
        
        Streptokinase [D08.811.277.656.300.775]
        
        Ubiquitin-Specific Proteases [D08.811.277.656.300.887]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        ADAM Proteins [D08.811.277.656.675.374.102]
        
        Botulinum Toxins [D08.811.277.656.675.374.153]
        
        Collagenases [D08.811.277.656.675.374.205]
        
        Endothelin-Converting Enzymes [D08.811.277.656.675.374.229]
        
        Gelatinases [D08.811.277.656.675.374.252]
        
        Insulysin [D08.811.277.656.675.374.300]
        
        Lysostaphin [D08.811.277.656.675.374.452]
        
        Matrix Metalloproteinases [D08.811.277.656.675.374.525]
        
        Mitochondrial Processing Peptidase [D08.811.277.656.675.374.563]
        
        Neprilysin [D08.811.277.656.675.374.600]
        
        PHEX Phosphate Regulating Neutral Endopeptidase [D08.811.277.656.675.374.616]
        
        Pregnancy-Associated Plasma Protein-A [D08.811.277.656.675.374.632]
        
        Procollagen N-Endopeptidase [D08.811.277.656.675.374.664]
        
        Pronase [D08.811.277.656.675.374.680]
        
        Thermolysin [D08.811.277.656.675.374.827]
        
        Metalloexopeptidases [D08.811.277.656.675.555]

Metalloendopeptidases Preferred

Metalloendopeptidases MeSH Descriptor Data 2025