- Concept UI
- M0017493
- Registry Numbers
- EC 3.4.24.-
- Scope Note
- A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.
- Terms
-
Pregnancy-Associated Plasma Protein-A
Preferred Term
Term UI
T536971
Date03/31/2003
LexicalTag
NON
ThesaurusID
NLM (2004)
-
IGFBP-4 Protease
Term UI
T259839
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2004)
-
IGFBP-4-Specific Proteinase
Term UI
T259840
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2004)
-
Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease
Term UI
T536972
Date03/31/2003
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Insulin-Like-Growth Factor Binding Protein-4 Protease
Term UI
T259841
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)
-
IGFBP-4 Metalloproteinase
Term UI
T259838
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2004)
-
PAPP-alpha
Term UI
T536976
Date03/31/2003
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Pregnancy Associated alpha Plasma Protein
Term UI
T033202
Date02/22/1979
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Pregnancy-Associated alpha-Plasma Protein
Term UI
T033203
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1980)
-
PAPP-A
Term UI
T033201
Date02/22/1979
LexicalTag
ABB
ThesaurusID
UNK (19XX)