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Procollagen N-Endopeptidase MeSH Descriptor Data 2026
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
Entry Term(s)
Procollagen N-Proteinase
Procollagen Peptidase
Registry Numbers
EC 3.4.24.14
Previous Indexing
Collagen (1966-1976)
Peptide Peptidohydrolases (1966-1976)
Protein Precursors (1973-1976)
Public MeSH Note
97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under PEPTIDE PEPTIDOHYDROLASES 1977-90)
History Note
97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under ENDOPEPTIDASES 1977-90)
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.