MeSH Browser

MeSH Heading: AAA Proteins
Tree Number(s): D08.811.277.040.013; D12.776.157.025
Unique ID: D000074582
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074582
Scope Note: A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 to 250 amino acid nucleotide-binding and catalytic domain, the AAA+ module. They assemble into hexameric ring complexes that function in the energy-dependent remodeling of macromolecules. Members include ATPASES ASSOCIATED WITH DIVERSE CELLULAR ACTIVITIES.
Entry Term(s): AAA Protein; AAA Superfamily; AAA+ Superfamily; P-Loop NTPases
Previous Indexing: Adenosine Triphosphatases (1995-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000626837
Scope Note: A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 to 250 amino acid nucleotide-binding and catalytic domain, the AAA+ module. They assemble into hexameric ring complexes that function in the energy-dependent remodeling of macromolecules. Members include ATPASES ASSOCIATED WITH DIVERSE CELLULAR ACTIVITIES.
Terms: AAA Proteins Preferred Term
Term UI T000914448
Date01/20/2017
LexicalTag ABX
ThesaurusID NLM (2018); AAA Protein
Term UI T001085046
Date07/20/2020
LexicalTag NON
ThesaurusID NLM (2022); AAA Superfamily
Term UI T000916553
Date03/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); AAA+ Superfamily
Term UI T000916552
Date03/01/2017
LexicalTag ABX
ThesaurusID NLM (2018)

AAA Proteins MeSH Descriptor Data 2025