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Follistatin MeSH Descriptor Data 2023


MeSH Heading
Follistatin
Tree Number(s)
D12.776.157.247
Unique ID
D038681
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D038681
Scope Note
A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
Entry Term(s)
Activin-Binding Protein
Registry Number
0
NLM Classification #
WK 515
Previous Indexing
Activins (2002)
Glycoproteins (1987-2001)
Inhibins (1987-2001)
Public MeSH Note
2003; was indexed under FOLLISTATIN (NM) 1988-2002
History Note
2003; use FOLLISTATIN (NM) 1988-2002
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2004/07/07
Follistatin Preferred
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