MeSH Browser

MeSH Heading: GTP-Binding Proteins
Tree Number(s): D08.811.277.040.330.300; D12.776.157.325; D12.776.476.338
Unique ID: D019204
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019204
Annotation: general or unspecified; prefer specifics; GTP stands for Guanosine TriPhosphate
Scope Note: Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.
Entry Term(s): G-Protein; G-Proteins; GTP-Binding Protein; GTP-Regulatory Protein; GTP-Regulatory Proteins; Guanine Nucleotide Coupling Protein; Guanine Nucleotide Regulatory Proteins
NLM Classification #: QU 55.2
Public MeSH Note: 1997; see G-PROTEINS 1985-1996; for G-PROTEINS see G-PROTEINS 1992-1999; for GUANINE NUCLEOTIDE REGULATORY PROTEINS see G-PROTEINS 1992-1996; for GTP-REGULATORY PROTEINS see G-PROTEINS 1985-1996
History Note: 1997(1985)
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0028608
Scope Note: Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.
Terms: GTP-Binding Proteins Preferred Term
Term UI T057212
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1997); G-Proteins
Term UI T018658
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1985); GTP-Binding Protein
Term UI T057211
Date09/13/1995
LexicalTag NON
ThesaurusID NLM (1997); GTP-Regulatory Protein
Term UI T057213
Date09/13/1995
LexicalTag NON
ThesaurusID NLM (1997); GTP-Regulatory Proteins
Term UI T057214
Date09/13/1995
LexicalTag NON
ThesaurusID NLM (1997); Guanine Nucleotide Coupling Protein
Term UI T057215
Date09/13/1995
LexicalTag NON
ThesaurusID NLM (1997); G-Protein
Term UI T018657
Date07/19/1988
LexicalTag NON
ThesaurusID UNK (19XX); Guanine Nucleotide Regulatory Proteins
Term UI T057216
Date09/13/1995
LexicalTag NON
ThesaurusID NLM (1997)

GTP-Binding Proteins MeSH Descriptor Data 2025