MeSH Browser

MeSH Heading: S-Phase Kinase-Associated Proteins
Tree Number(s): D12.776.157.743
Unique ID: D044786
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044786
Scope Note: A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS.
Entry Version: S PHASE KINASE ASSOC PROTEINS
Entry Term(s): S-Phase Kinase Associated Protein; SCF(SKP2); Skp Domain Protein; Skp Domain Proteins; Skp1 Protein; Skp1 Proteins; Skp2 Protein; Skp2 Proteins; p19 SKP1; p19(SKP1) Protein; p45 SKP2; p45(SKP2); p45(SKP2) Protein
Previous Indexing: Cell Cycle Proteins (1995-2003); Ligases (1983-2003)
Public MeSH Note: 2004; P19(SKP1)PROTEIN and P45(SKP)PROTEIN were indexed under CELL CYCLE PROTEINS 1995-2003
History Note: 2004; use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1983-2003; for P19(SKP1)PROTEIN and P45(SKP) PROTEIN use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1995-2003; for P45(SKP) use UBIQUITIN-PROTEIN LIGASES (NM) 1999-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0446233
Scope Note: A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS.
Terms: S-Phase Kinase-Associated Proteins Preferred Term
Term UI T534055
Date02/28/2003
LexicalTag NON
ThesaurusID NLM (2004); Skp Domain Proteins
Term UI T534056
Date02/28/2003
LexicalTag ABX
ThesaurusID NLM (2004); Skp Domain Protein
Term UI T534329
Date03/03/2003
LexicalTag ABX
ThesaurusID NLM (2004); S-Phase Kinase Associated Protein
Term UI T534330
Date03/03/2003
LexicalTag NON
ThesaurusID NLM (2004)

Concept UI: M0252305
Terms: Skp1 Proteins Preferred Term
Term UI T534385
Date03/04/2003
LexicalTag ABX
ThesaurusID NLM (2004); Skp1 Protein
Term UI T282308
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); p19 SKP1
Term UI T282309
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); p19(SKP1) Protein
Term UI T282310
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004)

Concept UI: M0446160
Terms: Skp2 Proteins Preferred Term
Term UI T534067
Date02/28/2003
LexicalTag ABX
ThesaurusID NLM (2004); p45(SKP2)
Term UI T401623
Date12/04/1999
LexicalTag ABX
ThesaurusID NLM (2004); Skp2 Protein
Term UI T460722
Date09/08/2001
LexicalTag ABX
ThesaurusID NLM (2004); p45 SKP2
Term UI T282306
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); p45(SKP2) Protein
Term UI T282307
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); SCF(SKP2)
Term UI T401622
Date12/04/1999
LexicalTag ABX
ThesaurusID NLM (2004)

S-Phase Kinase-Associated Proteins MeSH Descriptor Data 2025