MeSH Browser

MeSH Heading: Cyclins
Tree Number(s): D12.644.360.262; D12.776.167.218; D12.776.476.262
Unique ID: D016213
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016213
Annotation: note specifics
Scope Note: A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Entry Term(s): Cyclin
Previous Indexing: Invertebrate Hormones (1987-1990)
See Also: Maturation-Promoting Factor
Public MeSH Note: 93; was CYCLIN 1991-2
Online Note: use CYCLINS to search CYCLIN 1991-2
History Note: 93; was CYCLIN 1991-2
Date Established: 1991/01/01
Date of Entry: 1990/06/17
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Cyclins MeSH Descriptor Data 2025