MeSH Browser

MeSH Heading: Cyclin D
Tree Number(s): D12.644.360.262.150; D12.776.167.218.150; D12.776.476.262.150
Unique ID: D056741
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D056741
Scope Note: A cyclin subtype that is specific for CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. Unlike most cyclins, cyclin D expression is not cyclical, but rather it is expressed in response to proliferative signals. Cyclin D may therefore play a role in cellular responses to mitogenic signals.
Entry Term(s): Type D Cyclin; Type D Cyclins
Public MeSH Note: 2010; CYCLIN D was indexed under CYCLINS 1996-2009
History Note: 2010(1996)
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Cyclin D MeSH Descriptor Data 2025