NLM Logo

NLR Proteins MeSH Descriptor Data 2023


MeSH Heading
NLR Proteins
Tree Number(s)
D12.644.360.539
Unique ID
D000070576
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070576
Scope Note
Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.
Entry Term(s)
NLR Protein
NOD-like Receptor
NOD-like Receptors
Nucleotide-Binding Domain Leucine-Rich Repeat Protein
Nucleotide-binding Domain Leucine-rich Repeat Proteins
Registry Number
0
Previous Indexing
Nod Signaling Adaptor Proteins (2007-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2020/05/27
NLR Proteins Preferred
page delivered in 0.175s