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Nod Signaling Adaptor Proteins MeSH Descriptor Data 2023


MeSH Heading
Nod Signaling Adaptor Proteins
Tree Number(s)
D12.644.360.024.313
D12.644.360.539.500
D12.776.157.057.078
D12.776.476.024.391
Unique ID
D053472
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053472
Scope Note
Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance.
Entry Term(s)
NOD Leucine-Rich Repeat Proteins
NOD-LRR Signaling Adaptor Proteins
Nuclear-Binding Oligomerization Domain Proteins
Nucleotide Oligomerization Domain Proteins
Registry Number
0
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2016/03/30
Nod Signaling Adaptor Proteins Preferred
NOD Leucine-Rich Repeat Proteins Narrower
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